Septic shock pathophysiology authorstream presentation. Undifferentiated shock refers to the situation where shock is recognized but the cause is unclear. This was a nonrandomized, prospective observational study. Generally, an ebook can be downloaded in five minutes or less. Contents introduction definition classification pathophysiology stages of shock general features and effects of shock types of shock dental considerations in shock management of shock in dental office conclusion references 3 4.
Anaphylaxis has a variety of causes including foods, latex, drugs, and hymenoptera venom. Plasmainsulin and bloodglucose were measured before and after the intravenous injection of tolbutamide in patients with acute myocardial infarction. Find powerpoint presentations and slides using the power of, find free presentations research about pathogenesis of bacteria ppt. The pathogenesis involves a complex response of cellular activation that triggers the release of a multitude of proinflammatory mediators. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Cardiogenic shock occurs as a consequence of heart muscle or heart valve disease. Pathogenesis of dengue haemorrhagic fever and its impact. This viewpoint describes the pathogenesis of atherosclerosis with this ambitious goal in mind.
Chapter 20 shock pathogenesis of shock shock represents a diverse group of lifethreatening conditions common factor among all types of shock is hypoperfusion and impaired cellular oxygen utilization inadequate cellular oxygenation may result from. They may range from subclinical infection to dengue fever, dengue hemorrhagic fever dhf, and eventually dengue shock syndrome dss. The definition did not change much over the years, because the terms sepsis and septicaemia referred to several illdefined clinical conditions present in a patient with. Bailey and love shock is a term used to describe the clinical syndrome that develops when there is critical impairment of tissue perfusion due to some form. More than 1 million cases of shock are estimated to present to u. The species has been divided into 5 distinct types, ae. The new england journal of medicine n engl j med 365. Overview of shock pathophysiology ct1 education series intro slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Winner of the standing ovation award for best powerpoint templates from presentations magazine. Patients in circulatory shock showed a marked suppression of insulin secretion, compared with patients with uncomplicated myocardial infarction or with normal subjects.
Here, well be talking about cardiogenic shock, what it really is, and how it differs from the other types of shock. Definition, classification, etiology, and pathophysiology of shock in. Shock has different types, and the manifestations are different for every type. Chapter 20 chapter 20 shock pathogenesis of shock shock.
Rao md background in 1914, schottmueller wrote, septicaemia is a state of microbial invasion from a portal of entry into the blood stream which causes sign of illness. Ppt pathophysiology basics free download as powerpoint presentation. Shock is an acute widespread reduction in effective tissue perfusion that invokes an imbalance of oxygen supply and demand, anaerobic metabolism, lactic acidosis, cellular and organ dysfunction, metabolic abnormalities, and, if. Cardiogenic shok some notes develops in 10% to 20% of patients hospitalized ami mortality of such patients approximately 80% or higher very few patients develop shock immediately after ami about half of the patients develop shock within 24h pathology clinical signs ecg shows the pattern of ami or acute coronary insufficiency the sbp shock is a physiologic state characterized by systemic reduction in tissue perfusion, resulting in decreased tissue oxygen delivery. Important virulence factors encoded by these genes include fimbrial adhesins, enterotoxins, cytotoxins, capsule, and lipopolysaccharide, or lps. The more organs involved failing, the higher the mortality rate. A severe allergic reaction can lead to anaphylactic shock. Across section of a coronary artery cut just distal to a bifurcation. Classic and blastoid variants are recognized, the latter associated with inferior clinical outcome figure 1a. Despite advances in intensive care and supportive technology, the mortality rate of sepsis still ranges from 15% to 80%, reminding scientists and clinicians that it remains to be a major clinical challenge. A resurgence of invasive streptococcal diseases and rheumatic fever has appeared in outbreaks over the past 10 years, with a predominant m1 serotype as well as others identified with the outbreaks. Multiorgan dysfunction syndrome mods can be the end result of septic shock. View and download powerpoint presentations on shock pathology ppt. View and download powerpoint presentations on pathogenesis of bacteria ppt.
This inflammatory response causes activation of leukocytes. If you continue browsing the site, you agree to the use of cookies on this website. Clostridium perfringens is a grampositive, sporeforming, nonmotile, rodshaped organism commonly found in soil and in the intestines of humans and other animals. Pathogenesis and pathophysiology of dengue hemorrhagic fever. Ppt shock powerpoint presentation free to download. Aggressive replacement of volume while attending to the underlying etiology is the mainstay of treatment of hypovolemic shock. The mucus membrane colour may be bright red and animal may be hyperthermic. In a study carried out in abuth zaria, of 2940 medical admissions within the period of study, 42 were for mi and 6 of these patients went into cardiogenic shock. The major cause of unstability in polytrauma patients diagnosed by rush is hypovolemic shock 64%, followed by obstructive, whose second and third causes are respectively cardiogenic shock and. Pathophysiology and management of different types of shock. Find powerpoint presentations and slides using the power of, find free. Causes of septic shock as mentioned any type of bacteria in the bloodstream causes septic shock and this can occur from many infections, for example. A virotype is a particular combination of virulence genes.
Central or peripheral catheters for initial venous access of icu patients. Stages of shock deteriotion of the circulation in shock is a progressive phenomenon and can be devided arbitarily into 3 stages. Ppt cardiogenic shock powerpoint presentation free to. In europe, the prevalence rate of cardiogenic shock is approximately 7. Pathophysiology, recognition, and treatment roger f. Contents introduction definition classification pathophysiology stages of shock general features and effects of shock types of. Acsase medical student core curriculum shock shock is a life. Cardiogenic shock is an extremely morbid condition. Septic shock results when infectious microorganisms in the bloodstream induce a profound inflammatory response causing hemodynamic decompensation.
Role of clostridial toxins in the pathogenesis of gas. Summary group a streptococci are model extracellular grampositive pathogens responsible for pharyngitis, impetigo, rheumatic fever, and acute glomerulonephritis. Theyll give your presentations a professional, memorable appearance the kind of sophisticated look that todays audiences expect. Vasopressin versus norepinephrine infusion in patients with septic shock. Definition shock is a life threatening situation due to poor tissue perfusion with impaired cellular metabolism, manifested in turn by serious pathophysiological abnormalities. Viral disease is a sum of the effects on the host of virus replication and of the immune response. Improvement in their clinical condition was associated with a return to. The clinical presentation and diagnostic evaluation of undifferentiated shock and the evaluation of patients with specific forms of shock are. Worlds best powerpoint templates crystalgraphics offers more powerpoint templates than anyone else in the world, with over 4 million to choose from. Decreased cardiac output maldistribution of blood flow reduced blood oxygen content impaired tissue oxygenation results. Septic shock pathophysiology sepsis shock circulatory. Sepsis is an infectioninitiated systemic inflammatory syndrome with an estimated incidence of 18 million cases annually worldwide.
Ppt pathophysiology of circulatory shock powerpoint. Viral pathogenesis this lecture will define and discuss the basic principles of viral pathogenesis, the entire process by which viruses cause disease. Cardiogenic shock develops as a result of the failure of the heart in its function as a pump, resulting in inadequate cardiac output. Epidemiology septic shock, a form of distributive shock, is the most common form of shock among patients admitted to the intensive care unit, followed by cardiogenic and hypovolemic shock. Plasma leakage and intrinsic coagulopathy are the pathological hall marks in dengue haemorrhagic fever dhf. Summary much remains to be learned about the pathogenesis of the different manifestations of dengue virus denv infections in humans.
The presentation may be cryptic, as in the patient with compensated heart failure, or obvious as in the ultimate shock state of cardiac arrest. Worthley department of critical care medicine, flinders medical centre, adelaide, south australia abstract objective. As both cell tropism and tissue tropism of denv are considered major determinants in the pathogenesis of. Weve made a series of lectures talking about these types. Pathogenesis septic shock inflammatory response sirs immunosuppression cars concept of sepsis initiators innate immunity sirs. Despite recent advances in treatment, nearly 50% of patients with cardiogenic shock still do not survive to hospital discharge. When those with allergies are exposed to an allergen, their immune system can release chemicals that flood their system.
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